The collection consists of two volumes. The first notebook, "Notes of Queries to William Clark, with replies," (917.3.L58.b), contains Lewis' journal of the river trip from Pittsburgh to winter camp, August 30- December 12, 1803.

This item is Lewis' narrative journal of the river trip from Pittsburgh to the winter camp of the Lewis and Clark Expedition, together with meteorological observations. There are also entries by William Clark. Of the 126 leaves in this journal, 31 contain questions by Nicholas Biddle, with William Clark's replies, dated 1810. Includes parts II and III of Nicholas Biddle, "Notes on Indians...", and list of measurements of bones and other natural history specimens, in Lewis' hand. Also contains some sketches and two small maps.

These journals were kept while on the Lewis and Clark Expedition (1804-1806).

This diary is a journal of a trip from Philadelphia by stage to Pittsburgh, then afoot through Franklin, LeBoeuf, and Erie to the Huron River; thence by boat to Detroit, where he remained 26-29 July, when he set out by canoe for Michilimackinac. Included are descriptions of Detroit, plants, animals, springs, Indian mounds, and notes on goitre.

Meriwether Lewis and William Clark were explorers. This collection contains the manuscript journals kept by Lewis and Clark on their travels to the source of the Missouri River and across the continent to the Pacific Ocean. There are interlineations throughout by Nicholas Biddle, who published his narrative "History of the Expedition of Captains Lewis and Clark" (1814).